← Every GPUAMD · 32 or 16 GB VRAM · 1024 GB/s

What can the Instinct MI50 run?

With 32 GB, 8 of 12 popular open models fit. The best pick is Qwen3 32B at about 28 tok/s, about reading speed.

ollama run qwen3:32b

First time? Install Ollama, then paste that into a terminal. Is this your machine? Check it on the homepage.

16 GB VRAM

Every model the Instinct MI50 16 GB can run

5 of 12 fit. Best pick: gpt-oss 20B.

  • Qwen3 4BQuick everyday chat and summaries
    ~230 tok/s
    Runs greatqwen3:4b
  • Qwen3 8BA solid all-rounder for chat and writing
    ~110 tok/s
    Runs greatqwen3:8b
  • Gemma 3 12BReads images as well as text
    ~70 tok/s
    Runs greatgemma3:12b
  • Qwen3 14BNoticeably smarter at reasoning and code
    ~61 tok/s
    Runs greatqwen3:14b
  • gpt-oss 20BOpenAI's open model. Fast, strong reasoning
    ~180 tok/s
    Runs greatgpt-oss:20b
  • Gemma 3 27BGoogle's best open model for its size
    needs 19 GB
    Too biggemma3:27b
  • Qwen3 30B-A3B30B smarts at small-model speed
    needs 21 GB
    Too bigqwen3:30b
  • Qwen3 32BStrong coding and long answers
    needs 22 GB
    Too bigqwen3:32b
  • Llama 3.3 70BClose to the big cloud models
    needs 45 GB
    Too bigllama3.3:70b
  • gpt-oss 120BOpenAI's largest open model
    needs 67 GB
    Too biggpt-oss:120b
  • Qwen3 235B-A22BAlibaba's flagship open model, for multi-GPU rigs
    needs 144 GB
    Too bigqwen3:235b
  • DeepSeek R1 671BThe full DeepSeek R1, for the biggest rigs
    needs 406 GB
    Too bigdeepseek-r1:671b
32 GB VRAM

Every model the Instinct MI50 32 GB can run

8 of 12 fit. Best pick: Qwen3 32B.

  • Qwen3 4BQuick everyday chat and summaries
    ~230 tok/s
    Runs greatqwen3:4b
  • Qwen3 8BA solid all-rounder for chat and writing
    ~110 tok/s
    Runs greatqwen3:8b
  • Gemma 3 12BReads images as well as text
    ~70 tok/s
    Runs greatgemma3:12b
  • Qwen3 14BNoticeably smarter at reasoning and code
    ~61 tok/s
    Runs greatqwen3:14b
  • gpt-oss 20BOpenAI's open model. Fast, strong reasoning
    ~180 tok/s
    Runs greatgpt-oss:20b
  • Gemma 3 27BGoogle's best open model for its size
    ~33 tok/s
    Runs greatgemma3:27b
  • Qwen3 30B-A3B30B smarts at small-model speed
    ~180 tok/s
    Runs greatqwen3:30b
  • Qwen3 32BStrong coding and long answers
    ~28 tok/s
    Usableqwen3:32b
  • Llama 3.3 70BClose to the big cloud models
    needs 45 GB
    Too bigllama3.3:70b
  • gpt-oss 120BOpenAI's largest open model
    needs 67 GB
    Too biggpt-oss:120b
  • Qwen3 235B-A22BAlibaba's flagship open model, for multi-GPU rigs
    needs 144 GB
    Too bigqwen3:235b
  • DeepSeek R1 671BThe full DeepSeek R1, for the biggest rigs
    needs 406 GB
    Too bigdeepseek-r1:671b
Common questions

Can the Instinct MI50 run it?

Can the Instinct MI50 run Qwen3 30B-A3B?

Yes, with 32 GB or more. Qwen3 30B-A3B needs about 21 GB and the Instinct MI50 has 32 GB of VRAM. Expect about 180 tok/s, faster than you can read. The 16 GB version doesn't have room.

Can the Instinct MI50 run Qwen3 32B?

Yes, with 32 GB or more. Qwen3 32B needs about 22 GB and the Instinct MI50 has 32 GB of VRAM. Expect about 28 tok/s, about reading speed. The 16 GB version doesn't have room.

Can the Instinct MI50 run Llama 3.3 70B?

No. Llama 3.3 70B needs about 45 GB and the Instinct MI50 has at most 32 GB of VRAM. Ollama can still start it by putting part of the model in system RAM, but it runs several times slower. The most capable model it runs well is Qwen3 32B, at about 28 tok/s.

How we estimate

Generating a token reads the model's active weights from memory once, so speed is roughly memory bandwidth (1024 GB/s) divided by the active weight size, with efficiency calibrated on our own rack. Sizes are Ollama's default 4-bit downloads plus about 1.2 GB for context. Real results are usually within about a third. Measured one yourself? Send us the number.

Want something bigger?

The Ryzen AI Max+ 395 mini PC, 128 GB runs gpt-oss 120B at about 31 tok/s, from $3,400 used.

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